I. Introduction
Protein Structure : Polypeptide, and its 3-D conformation.
Protein sequence: 20 amino acids
Protein synthesis === Genetic Transcription + Translation
II. Genetic Transcription
DNA's information is copied onto mRNA, followed the base pairing rule: A ---> U, and G--> C
Triplet code:
Codon:
III. The Second Stage in Protein Synthesis ---- Translation
Translation:
Ribosome:
Transfer RNA (tRNA) :
DNA makes RNA make Protein.
Genetic code:
Redundancy and life's unity -----> Genetic code
A Closer Look at Protein Synthesis:
1. Protein synthesis begins: Transcription
RNA polymerase is responsible for the synthesis of new mRNA strand.
2. Messenger RNA processing
Introns:
Exons:
3. Structure of ribosomes:
4. Structure of transfer RNA:
5. Steps of Translation:
mRNA binds to ribosome
First tRNA arrives
Polypeptide chain is elongated: peptide bond formed, A site and P site.
Termination
of the growing chain, termination code: UAA, UAG, UGA.