1 selective affinities ___ (alter) during development
6 sound a snake makes
8 prefix meaning "toward"; as in cells will _ _vance over other cells when they adhere to them only lightly
10 _ _ _ _helium refers to the cellular organization in which cells are tightly connected to one another in sheets or tubes
11 epithelial cells can ___ (lose their connections and become individual cells) to form mesenchyme
14 if mixed cells interact to form an aggregate with the smallest interfacial free energy, they rearrange themselves into the most thermodynamically ___ pattern
16 big talk
17 adjacent cell surfaces _ _ _eract during development to localize cells in their proper sites within tissues and organs
19 insert an A for talk
20 an undergraduate degree, abbrev
21 to be contiguous or next to; one cell will ___ another cell and either adhere to it or move away from it
22 a thermodynamic ___ to explain sorting out is the differential adhesion hypothesis, in which the early embryo is viewed as existing in an equilibrium state until some changed gene activity alters the cell surface molecules; cells then move to restore an equilibrium
23 opposite of down
24 cells _ _cognize each other and extracellular matrix by using cell surface molecules
26 _ _ _ma_ cells are mesenchymal cells of the skin; if randomly mixed with epidermal cells they will migrate toward the center and reconstitute a histologically normal relationship
29 in the blastula, ___ (number) cells have the same affinity for each other
31 when amphibian embryo cells from different germ layers were recombined, in __ case did the cells remain randomly mixed
33 begin with a G to speak baby-talk, an M to speak cow-talk
34 _ _toderm is a germ layer that would assume an outside position in a sorting experiment
36 one way in which cells communicate with one another is by using ___ cues, soluble molecules that they secrete
40 a direction, abbrev
42 a heavy, radioactive substance, abbrev
43 _a_ Diego
44 morphogenesis requires changes in the composition of the cell _ _ _brane (surface); these changes can alter the adhesiveness of the cell and stimulate its movement
46 stop, or a goal
48 close or preferential association; differential cell affin_ _ _ is a dominant paradigm of morphogenesis
49 the __ (last) topography in cell aggregations is independent of the starting conditions
51 ocean
52 prefix meaning form, as in "_ _ _ _ _ _ _ _ _ogenesis is the development of organized multicellular arrangements such as tissues and organs."
54 _ _ bonucleic acid; _ _ bosome
56 preposition
58 that is, abbrev
59 a truth or datum
61 a cell ___ with other cells by adhering to them or by moving over them
64 making the _ _ more alkaline can dissociate embryonic amphibian tissues into single cells; normalizing it can then promote cell aggregation
65 extraterrestrial, one abbrev
66 a color
67 in the simplest form of the thermodynamic model, cells only need to have the same type of ____ (sticky substance) on their surfaces; in reality, cells have several types of adhesive molecules that change with time
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1 insert an O for police
2 prefix referring to tissue: if you mix dermal and epidermal cells, they will move to reconstruct a normal relation, an example of a _ _ _ _ _typic reaggregation
3 a phone company, abbrev
4 unintelligible or foolish talk
5 during sorting out, interactions form a _ _erarchy (ordered system) as though their associations are based on differential adhesions among cells
6 a person who secretly observes others to obtain information
7 if homotypic adhesions (A-A or B-B) are strong but heterotypic (A-B) adhesions are nonexistant, then mixed A and B cells will form ____ aggregates
8 add an S for a long-eared, patient, sure-footed mammal
9 a cellular process important to morphogenesis is the ___ and removal of cells
10 prefix meaning upon, on, over; as in "_ _ _dermal cells will envelop dermal cells when combined with them."
11 cells can individually _ _tach from epithelia, a process called _ _ lamination
12 as epithelial cells change ____ (form) and grow, they remain attached to one another
13 mutineer, insurrectionist
15 old, ancient, antique
18 a southwestern state, abbrev.
20 _ _bonic plague
25 a diffusible ___ that cells use to communicate could be a hormone, a growth factor or a morphogen
27 dissociated, individual cells that reaggregate in a rotary culture will form a _ _ _nd ball of cells because they maximize their adhesions with one another
28 in the sea urchin, vegetal blastula cells ___ their affinity for one another at the gastrulation stage while simultaneously acquiring affinity for protein fibrils inside the blastula
30 A and B cells sort out when the average strength of A-B adhesions is ___ than the average strength of A-A or A-B adhesions
31 a northern plains state, abbrev
32 if cells fail to adhere to one another, they will separate like ___ and water
35 many cells communicate by direct ____ with one another
37 the ___ (last) position of reaggregated cells from amphibian germ layers reflected their embryonic positions, with ectoderm surrounding mesoderm and endoderm residing in the innermost layer: somehow cells sort out into their proper positions
38 negative conjunction
39 in the sea urchin blastula, cells initially have a high affinity for their neighbors and for the outer extracellular hyaline ___; as this affinity weakens, they gain affinity for fibers in the blastocoel cavity and move inside it
41 embryonic cells do not _ _tain (keep) a single stable relationship with other cells; they alter their surfaces and change their affinity and interactions as development progresses
44 molecules secreted by cells will form an extracellular ____
45 microfilaments, abbrev
46 _ _doderm is a germ layer that would assume an innermost position in a sorting out experiment
47 development is a _ua_ (double) process requiring both differentiation of cells and their morphogenesis into intricate and precise arrangments
50 cells will _ _ _ _ _act sequentially with many different cells during development as their gene expression and the composition of their surfaces changes
51 a cellular process important to morphogenesis is changes in cell____ (form)
52 _ _ _enchyme refers to a cellular organization in which cells are unconnected to each other and operate as individual units
53 the ability of cell to _re_er (favor) adhesions with some cells more than with other cells is based on the balance of adhesion molecules on their surfaces
55 cells of two epithelia can merge with one another in a process called _ _ _ercalation
57 mine this, or a western state
58 during morphogenesis, a cell must reach its appropriate s_ _ _ (destination)
60 _ _anges in cell affinity are extremely important to the process of morphogenesis
62 cell surface molecules allow cells to _ _here to one another and to extracellular matrix
63 selective affinity among cells appears to be important for imparting position_ _ information to embryonic cells
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