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LINKS to more puzzles: Chapter 1 Chapter 2a Chapter 2b Chapter 3a Chapter 4a Chapter 4b Chapter 5a Chapter 5b |
LINKS to related sites: aCross Development home page: Tosney home page Society for Developmental Biology Gilbert’s textbook home page Sinauer |
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1 ten_ _ _in is a molecule resembling fibronectin, but it stimulates attachment in some cells and detachment in others 4 _ _ _ciclin is an immunoglobulin superfamily CAM first found in insects where it aids axon outgrowth 6 collagen constitutes nearly ___ the body protein (amount) 10 cytoplasmic protein that binds to integrins and to actin microfilaments 11 "_ _ ny" is an adjective that could describe the number of binding sites on laminin 12 a greeting 13 insert E for black, O for tiny, U to hang out 14 dirt 15 ___ lamina is a loose portion of the epithelial basal lamina that is secreted by mesenchymal cells 16 dispersal is a morphogenetic process in which an epithelium breaks ___ to form mesenchyme cells (preposition) 17 a proteoglycan has many disaccharides attached to a _o_e protein 18 pr_ _eoglycans are types of proteins with much more sugar than protein 19 a p_ _acrine signal is a diffusible signal that comes from adjacent cells, rather than through the blood 20 knock out, abbrev 21 mode of cell communication involving specific recognition between the surfaces of adjacent cells 24 an endocrine signal would travel through the blo_ _ 26 _ _D is the sequence in the laminin A chain that will bind an integrin receptor 27 disaccharides attach to a _or_ protein to make up a proteoglycan chain 29 a _ _talloproteinase is a secreted or cell surface enzyme that can selectively degrade extracellular matrix 31 the bas_ _ lamina is a type of extracellular matrix that forms a tight layer on one surface of epithelial cells 32 y_ _ and me 33 tenascin often inhibi_ _ cell adhesion rather than stimulating adhesion 34 dwarfism birth defect due to disruption in the RTK-Ras signaling pathway 38 a blas_e_a is a dedifferentiated mass of cells that forms at the tip of a regenerating salamander limb and develops to form appropriate distal tissues 39 the immunogoblu_ _ _ superfamily of CAMs is a class of cell adhesion molecules whose cell-binding domains resemble those of antibody molecules 41 medical doctor who is a generalist, abbrev 42 repeating disaccharide ("glycan") that has an amino group, abbrev 46 an affirmative 48 near, archaic 49 a G protein that, when activated by a ligand-bound receptor, is catalyzed from its normally inactive GDP-binding state, to form an active GTP-binding protein that transmits the signal 50 honest ____ 53 activating the inosit_ _ phosphate signal transduction path drastically changes cell physiology by releasing calcium ions from the endoplasmic reticulum 54 glycosaminoglycans can retain and present _r_wth factors to cellular receptors 55 CAMs are _ _ _ _ _ _globulin superfamily class of cell adhesion molecules whose cell-binding domains resemble those of antibody molecules 57 extracellular matrix forms a ___ (mesh) of insoluble molecules outside cells 59 midwest state that also comes in a Northern form 60 _e_l_ne; to lay down; _e_e_ve; to get 62 during dispersal, epithelial cells will ___ their connections with one another and become single cells 66 the other one, personal 67 molecular components of the cytoskeleton that bind talin and alpha-actinin 68 an _ _ _ _ _rine signal is released by cells into the blood, where it is available for any cell that has a receptor to it 69 _ _ _inin is a substrate adhesion molecule made of three peptide chains that can bind to collagen, glycosaminoglycans and cells |
2 what some migrating cells will do if fibronectin is removed 3 _ _ _herins are a class of cell adhesion molecules whose cell-adhesive properties depend on calcium ions 4 _ _ _ _ _nectin is a large glycoprotein dimer with multiple binding sites that can link cells to collagen and proteoglycans, and link extracellular matrix elements to one another 5 a differentiation _ _tigen is a membrane component typical of particular tissues or stages, recognizable by antisera 6 alp_ _ ac_inin is a cytoplasmic protein that binds to integrins and to actin microfilaments 7 g_ _ _ _n is another term for a disaccharide 8 type of collagen specific for basal lamina 9 junction molecules in the plasma membrane form ___ connections; they provide mechanical strength in epithelia 11 _ _ _ _ _ _ _proteinases can be secreted or linked to the cell surface 13 family of kinases that activate STAT transcription factors 14 _ _ _strate adhesion molecules molecules bind cells to their extracellular matrices, including cell surface receptors and matrix components 15 decay 17 send a copy to, abbrev 22 amount of signal a ligand will induce when excess mutant receptor is present 23 utensil, implement 25 integrins have ___ functions, since they bind both outside and inside the cell (number of roles) 26 during dispe_ _ _l an epithelium converts to a mesenchyme 27 complex proteins inside the cell that anchor cadherins 28 extracellular matrix (abbrev) 29 _ _ _ _ _ _genesis is the creation of multicellular arrangements to make tissues and organs 30 collag_ _ is a major structural support for most animal organs 31 if cells lacked the ability to _dhe_e to one another, we would all be single-celled organisms 33 size of a gap junction connection between cells 35 metalloproteinases can selectively ___ extracellular matrix 36 integrins s_ _n (cross) the plasma membrane and therefore integrate extracellular and intracellular scaffolds 37 yes, foreign 40 important to binding of cadherins but not of CAMs 41 to a_ _re_a_e is the ability of randomly mixed cells to sort out and clump together 43 double a 4.0 44 graduate student instructor, abbrev 45 proteins involved in cell-cell adhesions, uniting cells into epithelia or mesenchymal aggregates and assuring separation of different cells and tissues, abbrev 47 add an N and get a long time 51 source of further growth and development, particularly in plants 52 _ _docrine signal is a blood-borne diffusible molecule that can initiate a reaction 56 in signal transduction, binding of a ligand to a receptor can cause the cytoplasmic domain of the receptor to be phosph_ _ _ _lated 58 delamination is a morphogenetic process in which cells _ _ _ape from an epithelium and form mesenchyme 61 the basal lamina will _ _ _t (cover) the basal surface of epithelia 62 complex molecular border surrounding eukaryotic cells, composed of a fluid lipid _ _layer containing proteins that interact with the outer and inner environments 63 nurse 64 plural ending for more than one basal lamina 65 insert an E to know TOP |
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